Levi Winston Taylor is a shameless piece of shit. He has given up on his academic dreams, neglected his friends, terrified his fellow citizens and has abandoned all forms of sobriety. Happiest when drinking and spewing bile, Levi hates everyone almost as much as he hates himself due to his deforming genetic disorder known as ectrodactyly or "Lobster Claw Syndrome". His only friends are Courtney, the self-loathing girlfriend he despises, and Lucas, his last childhood friend who refuses to give up on Levi. One day Lucas introduces Levi to his new girlfriend Jane – a sharp, no nonsense, semi-deaf professor who seems immune to Levi’s barbs. Levi is instantly challenged and attracted to her. However, Levi’s admiration quickly degenerates into an unhealthy obsession that confuses romantic love with depraved sex and bottomless need.